Hi All,

Dropping a quick research roundup below. If you’re looking for a suggestion on where to start, this paper stood out to me: Biomimetic lung-on-a-chip to model virus infection and drug evaluation

In it, the authors provide a broad level review of various different Lung-Chip models and how they’ve been used in the study of viral inf… Read more

Hi All,

Evidently this past week was the time to publish reviews! We’ve got a long list of what seems like great research below, so let’s just cut straight to it:

Reminder: If you haven’t already done it, be sure to check out our Water Cooler Chat forum as well as our Perspectives forum for some general discussions from the indus… Read more

November 16, 2022 is COPD World Day. According to the World Health Organization (WHO), chronic obstructive pulmonary disease – a lung disease that makes it difficult to breathe – is the third leading cause of death worldwide, causing 3.23 million deaths in 2019. It includes emphysema and chronic bronchitis and most often results from smoking, lon… Read more

Watch your step here, I’ve just dropped the past week’s publications on Vascular 3D systems.

Also, an obligatory reminder that this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Read more

Watch your step here, I’ve just dropped the past week’s publications on Tumor 3D systems.

Also, an obligatory reminder that this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Read more

Watch your step here, I’ve just dropped the past week’s publications on Heart 3D systems.

Also, an obligatory reminder that this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Read more

Watch your step here, I’ve just dropped the past week’s publications on Lung 3D systems.

Also, an obligatory reminder that this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Read more

Watch your step here, I’ve just dropped the past week’s publications on Liver 3D systems.

Also, an obligatory reminder that this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Read more

Watch your step here, I’ve just dropped the past week’s publications on Intestine 3D systems.

Also, an obligatory reminder that this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Read more

Watch your step here, I’ve just dropped the past week’s publications on Heart 3D systems.

Also, an obligatory reminder that this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with… Read more

Watch your step here, I’ve just dropped the past week’s publications on Eye 3D systems.

Also, an obligatory reminder that this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with… Read more

Here you can find a collection of some of the latest publications on Brain 3D systems. For all Organ-Chip publications, check out the Journal Club Forum!

This is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

October 2022 publications:

• Approaches t…

Read more

Hi All,

Dropping this week’s research roundup a bit early this week thanks to a busy day tomorrow. Nonetheless, this feels like a particularly good group. There’re more than a few interesting reviews, and a few articles that are particularly relevant to the ethics of organoid research (if this interests you, definitely hop over to the Frankenstein… Read more

Also, forgot to mention that last week I stumbled onto this paper while putting together a research roundup: Check it out and lmk if it prompts any thoughts, scientific or otherwise.

Small tissue chips with big opportunities for space medicine

In 1969, astronaut Neil Armstrong made history as the first person to walk on the moon. As he put his left foot onto the ground, he said “That’s one small step for man, one giant leap for mankind.”

For more than half a century, NASA has been exploring space and making discoveries that not only impact our planet and the universe, but all of… Read more

@Chris — That makes a lot of sense. Is there any benchmark for determining what minimum criteria the model should meet? For example, if the Gut-Chip shows signature cytokine and permeability responses, but is lacking a cell-surface biomarker, would the model be invalidated or just caveated? Not sure if that example makes complete sense, but I’m… Read more

Just curious if anyone here is going to be at ASHG and if so, are you presenting a poster or talk? If you are, consider posting a link to your abstract or your poster/talk number.

 

Thanks!

Forgot to add this one:

• Impact of Non-Muscle Cells on Excitation-Contraction Coupling in the Heart and the Importance of In Vitro Models

Dropping off the past week’s research on Vascular 3D systems As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with that, on to the list:

• Live imaging of nitri…

Read more

Dropping off the past week’s research on Tumor 3D systems As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with that, on to the list:

• TP53 R249S mutation in he…

Read more

Dropping off the past week’s research on Reproductive 3D systems As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with that, on to the list:

• Mice 3D testi…

Read more

Dropping off the past week’s research on Musculoskeletal 3D systems As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with that, on to the list:

• …

Read more

Dropping off the past week’s research on Lung 3D systems As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with that, on to the list:

• Functional Trachea Recon…

Read more

Dropping off the past week’s research on Liver 3D systems As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with that, on to the list:

• Facile suspension cultu…

Read more

Dropping off the past week’s research on Kidney 3D systems As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with that, on to the list:

• Discriminating bladd…

Read more

Dropping off the past week’s research on Intestine 3D systems As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with that, on to the list:

• Canine intestinal organ…

Read more

Dropping off the past week’s research on Brain 3D systems As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with that, on to the list:

• Live imaging of nitri…

Read more

Dropping off the past week’s research on Brain 3D systems As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with that, on to the list:

• Molecular pathology of Us…

Read more

Dropping off the past week’s research on Brain 3D systems As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with that, on to the list:

• Reconstruction of ovine…

Read more

Dropping off the past week’s research on Stem Cells and Bone Marrow 3D systems As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(If you want to see the whole list, check out the Journal Club Forum)

And with that, on to the list:

Read more

Hi All,

It’s that time of week again. Here’s some light reading for ya’ll as you go into the weekend. (Protip – I’ve found the Toby chrome extension to be super helpful for saving my computer’s RAM. You can easily save tabs by groups with the extension. My “to read” group is as expansive as the concept of infinity.)

If you haven’t already… Read more

“I collected the instruments of life around me, that I might infuse a spark of being into the life-less thing that lay at my feet.” – Victor Frankenstein, disgraced scientist.

Between Dia De Los Muertos and Halloween, this time of year is marked by a celebration of both life and death, as well as musings about the blurry boundary separating the… Read more

It seems that, every year, there is a short flurry of headlines about de-extinction efforts. Sometimes it’s centered on the possibility that woolly mammoths may one day walk among us again. Other times it’s the thylacine, or—less dramatically—the carrier pigeon.

The theoretical merits of these efforts can be explored, and much ink has been spi… Read more

What will it take to dethrone animal models as the gold standard in preclinical drug testing?

For almost a century, animals have served as the last line of defense in drug development, and for good reason: unlike in vitro systems, living animals have interconnected organ systems and complex tissues that interact with—and potentially a… Read more

Hi All,

Me again. Dropping off the past week’s research on tumor 3D systems. As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(Also, you’ll see this text throughout Moxi as I divide papers up into their respective tissue Forums. Sorry… Read more

Hi All,

Me again. Dropping off the past week’s research on lung 3D systems. As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(Also, you’ll see this text throughout Moxi as I divide papers up into their respective tissue Forums. Sorry in… Read more

Hi All,

Me again. Dropping off the past week’s research on renal 3D systems. As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(Also, you’ll see this text throughout Moxi as I divide papers up into their respective tissue Forums. Sorry in… Read more

Hi All,

Me again. Dropping off the past week’s research on intestinal 3D systems. As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(Also, you’ll see this text throughout Moxi as I divide papers up into their respective tissue Forums. Sor… Read more

Hi All,

Me again. Dropping off the past week’s research on heart/cardiovascular 3D systems. As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(Also, you’ll see this text throughout Moxi as I divide papers up into their respective tis… Read more

Hi All,

Me again. Dropping off the past week’s research on brain/neuronal 3D systems As a reminder, this is just a sampling that is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in the comments below!

(Also, you’ll see this text throughout Moxi as I divide papers up into their respective tissue For… Read more

Hi All,

Here again with another research roundup. Based on some feedback and the volume of studies coming out, I’m going to be curating this list to reduce the overall number but, hopefully, enriching it for interesting content. Admittedly the selection is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in… Read more

Noticed this listing while searching for related topics. In case anyone is looking, JD and link below:

The department of Cell Biology-Inspired Tissue Engineering (cBITE) at the MERLN Institute for Technology-inspired Regenerative Medicine at Maastricht University in the Netherlands invites applications for a post-doctoral position. The… Read more

Hi All,

Here again with another research roundup. Based on some feedback and the volume of studies coming out, I’m going to be curating this list to reduce the overall number but, hopefully, enriching it for interesting content. Admittedly the selection is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in… Read more

Hi All,

Here again with another research roundup. Based on some feedback and the volume of studies coming out, I’m going to be curating this list to reduce the overall number but, hopefully, enriching it for interesting content. Admittedly the selection is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in… Read more

Hi All,

Here again with another research roundup. Based on some feedback and the volume of studies coming out, I’m going to be curating this list to reduce the overall number but, hopefully, enriching it for interesting content. Admittedly the selection is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in… Read more

Hi All,

Here again with another research roundup. Based on some feedback and the volume of studies coming out, I’m going to be curating this list to reduce the overall number but, hopefully, enriching it for interesting content. Admittedly the selection is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in… Read more

Hi All,

Here again with another research roundup. Based on some feedback and the volume of studies coming out, I’m going to be curating this list to reduce the overall number but, hopefully, enriching it for interesting content. Admittedly the selection is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in… Read more

Hi All,

Here again with another research roundup. Based on some feedback and the volume of studies coming out, I’m going to be curating this list to reduce the overall number but, hopefully, enriching it for interesting content. Admittedly the selection is largely based on titles and abstracts, so if I’ve missed a cool article, please drop it in… Read more